Cancer is commonly complicated by psychiatric comorbidity, particularly dep
ression. However, the effects of panic on cancer treatment and cancer patie
nts' quality of life are not well understood. To examine more closely the o
ccurrence of panic attacks and panic disorder in cancer patients, we retros
pectively reviewed charts of 106 consecutive psychosomatic consultations of
inpatients with cancer at a regional cancer center. Approximately one-fift
h of the patient sample presented with panic attacks or panic disorder at t
he time of the consultation. We present four case examples to demonstrate t
he potential effect of panic on cancer patients, including requests for can
cer treatment discontinuation. We report resolution of panic with benzodiaz
epine and selective serotonin reuptake inhibitors. Copyright (C) 2000 John
Wiley & Sons, Ltd.