The study aimed to determine whether occupational contact urticaria an
d symptoms of mucous membranes, reported by five workers in a cactus n
ursery, were due to IgE-mediated allergy to Schlumbergera cacti. The f
ive persons had positive skin prick tests to the plants as is and posi
tive histamine-release tests, and in three of them specific IgE to the
cacti could be demonstrated by Maxisorp RAST and immunoblotting. Four
of the patients were atopic, and the fifth had a positive skin prick
test to cat dander, indicating latent atopy Skin prick tests with cact
i were negative in most atopic volunteers, and all had negative histam
ine-release tests. The results suggest a true IgE-mediated allergy to
the cacti, and both genetic predisposition and close contact with the
plants at work seem to be important factors in the emergence of this n
ew occupational allergy.