We consider a system modeling the flow of nematic liquid crystals with vari
able degrees of orientation. Although the set of constitutive equations inv
olves many different parameters, the flow behavior is determined mostly by
three nondimensional parameters, i.e., the Ericksen number, the Reynolds nu
mber, and the interface number. We establish a dissipative relation of the
system in general domains. In the case of plane Poiseuille flow, we prove e
xistence and regularity of solutions. Moreover, we discuss the stationary c
onfigurations with a large number of defects due to the large Ericksen numb
er of the flow.