Radiofrequency (pacing and thermic effects) in the treatment of sleep-disordered breathing

Citation
C. Guilleminault et al., Radiofrequency (pacing and thermic effects) in the treatment of sleep-disordered breathing, SLEEP, 23, 2000, pp. S182-S186
Citations number
26
Categorie Soggetti
Neurosciences & Behavoir
Journal title
SLEEP
ISSN journal
01618105 → ACNP
Volume
23
Year of publication
2000
Supplement
4
Pages
S182 - S186
Database
ISI
SICI code
0161-8105(20000615)23:<S182:R(ATEI>2.0.ZU;2-9
Abstract
Radiofrequency, whether it is used for pacing or for its thermal liberation properties, has been investigated as a treatment for sleep-disordered brea thing. Diaphragmatic pacing has a long history. The problems associated wit h pacing, which are related to patient selection, equipment failure, distur bances at the electrode/nerve interface, neuromuscular function failure, mu scle fatigue, and the physiological consequences of stimulation, will have to be resolved with XIIth nerve stimulation. Radiofrequency thermal ablatio n has been applied on the tongue of an animal model. In man, turbinates, so ft palate tissue and the base of tongue have been treated. These feasibilit y studies have demonstrated that obstructive sleep apnea syndrome and upper airway resistance syndrome can be completely controlled using radiofrequen cy thermal ablation in some subjects. These results can be obtained without complications related to speech, taste or swallowing. The treatment can be administered as an outpatient procedure, but many applications are needed, and treatment may span 6 months. Too high a level of radiofrequency will c ause pain or otherwise avoidable complications. The determination of which patients will benefit most from these procedures will require further multi -center, placebo-controlled studies.