ISOFENPHOS POISONING - PROLONGED INTOXICATION AFTER INTRAMUSCULAR INJECTION

Case Report: We report a unique case of attempted suicide by intramusc ular injection of the organophosphate isofenphos which resulted in a m uscarinic and nicotinic syndrome lasting 15 days and requiring prolong ed mechanical ventilation and hospitalization. The patient, who demons trated no signs of delayed polyneuropathy on hospital day 25, subseque ntly died of pneumonia. Toxicological investigations showed isofenphos plasma decay and confirmed the intramuscular route of poisoning. We b elieve continuous isofenphos absorption resulted in the prolonged into xication observed in this patient.