A novel and convenient synthesis of 2-amino-3-cyano-5-N-substituted piperazinyl pyridines

Authors
Rao, VS Gupta, SVSAK Giridhar, P Reddy, BS
Citation
Vs. Rao et al., A novel and convenient synthesis of 2-amino-3-cyano-5-N-substituted piperazinyl pyridines, SYN COMMUN, 30(14), 2000, pp. 2625-2628
Citations number
14
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
30
Issue
14
Year of publication
2000
Pages
2625 - 2628
Database
ISI
SICI code
0039-7911(2000)30:14<2625:ANACSO>2.0.ZU;2-N
Abstract
A mixture of two moles of triethylorthoacetate, one mole of malononitrile a nd one mole of N-substituted piperazine in the presence of excess of ammoni um acetate at reflux conditions affords the title compounds. Elemental and spectral data confirms the structures of the purified compounds.