Application of an ion-selective field effect transistor with a photocured polymer membrane in nephrology for determination of potassium ions in dialysis solutions and in blood plasma

Application of a potassium ion sensor based on an ion sensitive field effec t transistor (ISFET) for ion control of a dialysis solution in an artificia l kidney and in blood plasma of patients treated by hemodialysis is present ed. Sensors and their long-term stability were characterised in constant co ntact with test solutions. Test results are compared to those obtained with conventional ion-selective electrodes and commercial blood ion analyser. T ested ISFET sensors showed high reliability in potassium ion measurements i n the physiologically significant concentration range which, along with low cost of their production, makes them promising for cited application. (C) 2000 Elsevier Science B.V. All rights reserved.