Enzymatic acylation of cyclobutene and cyclobutane meso-diols at low temperature

Citation
C. Pichon et al., Enzymatic acylation of cyclobutene and cyclobutane meso-diols at low temperature, TETRAHEDR-A, 11(11), 2000, pp. 2429-2434
Citations number
18
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
11
Issue
11
Year of publication
2000
Pages
2429 - 2434
Database
ISI
SICI code
0957-4166(20000616)11:11<2429:EAOCAC>2.0.ZU;2-A
Abstract
Acylation of cyclobutane and cyclobutene diols 5 and 8 in the presence of P seudomonas fluorescens lipase below room temperature led to monoacetates ()-6 and (-)-9, respectively. The chemical yields and enantiomeric excesses were nearly quantitative. (C) 2000 Elsevier Science Ltd All rights reserved .