A 41 year old woman presented with community acquired pneumonia (CAP) which
failed to resolve following treatment with amoxycillin and cefaclor prior
to referral. Quantitative culture of sputum revealed a pure growth. of Haem
ophilus parainfluenzae and, following antibiotic susceptibility testing of
the isolate, ciprofloxacin was prescribed resulting in resolution of the in
fection. Immunological investigations showed that the patient had a high ti
tre of H parainfluenzae specific IgM. The combination of a pure growth of H
parainfluenzae, a response to appropriate antimicrobial therapy, and the p
resence of a specific antibody response indicated that this organism had a
pathogenic role in the patient's pneumonia and should be considered in the
differential diagnosis of CAP.