Objective: To evaluate the accuracy of the Brugada algorithm for analysis o
f wide-complex tachycardia (WCT) when applied by board-certified emergency
physicians and board-certified cardiologists. Methods: A database consistin
g of 157 electrocardiograms of WCTs were evaluated in a blinded fashion usi
ng the Brugada criteria to determine the presence of ventricular tachycardi
a (VT) or supraventricular tachycardia with aberrancy. These results were t
hen compared with the electrophysiologically proven diagnosis for each trac
ing. Sensitivity and specificity of the Brugada criteria for diagnosis of V
T were calculated. Two board-certified emergency physicians and two board-c
ertified cardiologists analyzed each tracing, and interobserver agreement w
as determined using the kappa statistic. Results: Sensitivity and specifici
ty for the determination of VT using the Brugada algorithm were 85% [95% co
nfidence interval (95% CI) = 79% to 91%] and 60% (95% CI = 43% to 78%) for
cardiologist 1 (C 1) and 91% (95% CI = 86% to 96%) and 55% (95% CI = 37% to
72%) for C 2. Emergency physician (EP 1) achieved a sensitivity of 83% (95
% CI = 78% to 91%) and a specificity of 43% (95% CI = 25% to 59%), while EP
2 attained 79% (95% CI = 73% to 87%) and 70% (95% CI = 51% to 84%), respec
tively. The original authors achieved a sensitivity of 98.7% and specificit
y of 96.5% when determining VT in their study population. Interobserver agr
eement for the emergency physicians and the cardiologists in determining VT
was 82% and 81%, respectively. Conclusions: Neither the emergency physicia
ns nor the cardiologists were able to achieve a sensitivity or specificity
as high as that reported by the original investigators when using the Bruga
da algorithm to determine the presence of VT.