The aim of this paper is to review the existing literature on the inci
dence, morbidity and mortality of lower limb amputation. The functiona
l level of the lower limb amputee and the predictive factors for funct
ioning with a prosthesis are reviewed, both for unilateral and for bil
ateral amputees. The reported incidence of lower extremity amputation
(LEA) varies considerably between different Western countries. The mea
n survival of LEA patients ranges between two and five years. Assessme
nt of functional outcome is carried out differently. Studies are not c
omparable and most concern selected groups of amputees. Increasing age
, concurrent disease and poor compliance are prognostic factors for a
low functional level. For optimal planning of rehabilitation it is nec
essary to study a complete cohort of amputees with respect to these pr
ognostic factors.