Long-term morbidity and mortality from hypertension are more closely relate
d to home than to casual office blood pressure levels. There is no generall
y accepted recommendation on how to best schedule home blood pressure (HBP)
recordings, perhaps because the effect of varying the home monitoring sche
dule on the HBP average is not well studied. The goals of this analysis are
to describe the effects of HBP monitoring schedules on the accuracy of res
ultant HBP averages and to determine which monitoring schedule parameters c
orrelate with HBP accuracy. Twelve published studies, each including home,
office, and awake ambulatory blood pressure means were identified. Accuracy
of office and HBP averages were determined by their agreement with corresp
onding awake ambulatory averages. Variations in HBP monitoring schedule par
ameters did not significantly affect the accuracy of the resultant HBP aver
ages among the studies. In univariate analyses, no individual parameter cor
related significantly with the final HBP average accuracy. As the total num
ber of HBP readings obtained increased, or as other monitoring schedule par
ameters intensified, the superior accuracy of HBP levels as compared to tha
t of casual office values also failed to significantly improve. No HBP accu
racy differences were found among groups characterized by different HBP sch
edule parameter ranges. In conclusion, the accuracy of HBP measurements, as
determined by their agreement with an awake ambulatory mean, is maintained
regardless of substantial variations in HBP monitoring schedules. Therefor
e, the majority of the benefits derived from HBP monitoring will likely be
achieved by obtaining only a few HBP measurements using a minimally complex
monitoring schedule. Am J Hypertens 2000; 13:625-631 (C) 2000 American Jou
rnal of Hypertension, Ltd.