OBJECTIVE: We hypothesized that maternal birth weight was associated with t
he risk of cesarean delivery for nulliparous women.
STUDY DESIGN: In a population-based cohort study, maternal birth data were
linked to a Washington State database, including the birth certificates of
18,905 first-born singleton infants (1987-1995).
RESULTS: Among non-Hispanic white subjects, maternal birth weight of 2500 t
o 3999 g was associated with a 20.9% risk of cesarean delivery. which was t
he lowest risk, compared with 24.5% for a maternal birth weight <2500 g (P
< .05) and 24.0% for a maternal birth weight greater than or equal to 4000
g (P < .05). Similar patterns of risk were noted among Hispanic and Native
American subjects. although the associations did not reach statistical sign
ificance. Risk of cesarean delivery was not associated with maternal birth
weight among African American subjects. Among non-Hispanic white subjects,
the risk of cesarean delivery was 3.23 times greater with a maternal birth
weight <2500 g and an infant birth weight greater than or equal to 4000 g c
ompared with pregnancies with both maternal and infant birth weights betwee
n 2500 and 3999 g (P < .001). Adjustment for socioeconomic factors did not
alter these results.
CONCLUSION: Low and high maternal birth weights exert an intergenerational
risk of cesarean delivery in nulliparous non-Hispanic white women.