A patient with chronic thromboembolic pulmonary hypertension and heparin-in
duced thrombocytopenia successfully underwent pulmonary thromboendarterecto
my with circulatory arrest, using recombinant hirudin as an alternative ant
icoagulant to heparin. Techniques for administration as well as monitoring
of this drug's effects are discussed. (C) 2000 by The Society of Thoracic S
urgeons.