Cloning and sequence of the gene encoding a novel cefetoxime-hydrolyzing beta-lactamase (CTX-M-9) from Escherichia coli in Spain

Authors
Sabate, M Tarrago, F Navarro, F Miro, E Verges, C Barbe, J Prats, G
Citation
M. Sabate et al., Cloning and sequence of the gene encoding a novel cefetoxime-hydrolyzing beta-lactamase (CTX-M-9) from Escherichia coli in Spain, ANTIM AG CH, 44(7), 2000, pp. 1970-1973
Citations number
21
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
44
Issue
7
Year of publication
2000
Pages
1970 - 1973
Database
ISI
SICI code
0066-4804(200007)44:7<1970:CASOTG>2.0.ZU;2-U
Abstract
A new CTX-M-type beta-lactamase (CTX-M-9) has been cloned from a clinical c efotaxime-resistant Escherichia coli strain. Despite the close identity tha t exists between the CTX-M-9 and Toho-2 beta-lactamases (88%), the 35 amino acids located between residues Ala-185 and Ala-219 are totally different i n both enzymes. Outside of this region there are only six amino acids subst itutions between both proteins.