Tolerance of Aedes aegypti larvae to triorganotins

The effects of triorganotins on the 4th instar stage of Aedes aegypti larva e were evaluated. The most effective of the 15 triorganotins used in the st udy was tributyltin chloride with an LC50 value of 0.57 +/- 0.07 mg dm(-3) The low LC50 values obtained indicated that this class of compounds is an e ffective larvicide against the larvae of this species of mosquito. The toxi city of the compounds was found to be primarily dependent oil the R group a ttached to the tin atom. The order of activity for the triorganotins tested was Bu>Ph>Cy>Me. However, a limited order, based on two series of the comp ounds tested, was also observed for the anionic X group on the tin atom, Co pyright (C) 2000 John Wiley & Sons, Ltd.