With high-sensitivity imaging arrays, accurate calibration is essential to
achieve the limits of detection of space observatories. One can simultaneou
sly extract information about the scene being observed and the calibration
properties of the detector and imaging system from redundant dithered image
s of a scene. There are large differences in the effectiveness of dithering
strategies for allowing the separation of detector properties from sky bri
ghtness measurements. In this paper, we quantify these differences by devel
oping a figure of merit (FOM) for dithering procedures based on their usefu
lness for allowing calibration on all spatial scales. The figure of merit m
easures how well the gain characteristics of the detector are encoded in th
e measurements, and is independent of the techniques used to analyze the da
ta. Patterns similar to the antenna arrangements of radio interferometers w
ith good u-nu plane coverage are found to have good figures of merit. We pr
esent patterns for both deep surveys of limited sky areas and for shallow s
urveys. By choosing a strategy that encodes the calibration in the observat
ions in an easily extractable way, we enhance our ability to calibrate our
detector systems and to reach the ultimate limits of sensitivity that are r
equired to achieve the promise of many missions.