Cloning and characterization of a novel RNA-binding protein SRL300 with RSdomains

Authors
Sawada, Y Miura, Y Umeki, K Tamaoki, T Fujinaga, K Ohtaki, S
Citation
Y. Sawada et al., Cloning and characterization of a novel RNA-binding protein SRL300 with RSdomains, BBA-GENE ST, 1492(1), 2000, pp. 191-195
Citations number
14
Categorie Soggetti
Molecular Biology & Genetics
Journal title
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
ISSN journal
01674781 → ACNP
Volume
1492
Issue
1
Year of publication
2000
Pages
191 - 195
Database
ISI
SICI code
0167-4781(20000621)1492:1<191:CACOAN>2.0.ZU;2-S
Abstract
AT-rich element binding factor 1 (ATBF1) mRNA encodes a transcription facto r implicated in neuronal differentiation. A cDNA for the protein that can b ind the 5'-noncoding sequence of the ATBF1 mRNA was cloned. The deduced pro tein, termed SRL300, contains a unique RNA-binding region, two large RS dom ains and many phosphorylation sites. SRL300 protein was detected in both hu man and rat cells. (C) 2000 Elsevier Science B.V. All rights reserved.