The human SOX18 gene: cDNA cloning and high resolution mapping

Authors
Stanojcic, S Stevanovic, M
Citation
S. Stanojcic et M. Stevanovic, The human SOX18 gene: cDNA cloning and high resolution mapping, BBA-GENE ST, 1492(1), 2000, pp. 237-241
Citations number
35
Categorie Soggetti
Molecular Biology & Genetics
Journal title
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
ISSN journal
01674781 → ACNP
Volume
1492
Issue
1
Year of publication
2000
Pages
237 - 241
Database
ISI
SICI code
0167-4781(20000621)1492:1<237:THSGCC>2.0.ZU;2-3
Abstract
SOX genes comprise a family of genes that are related to the mammalian sex determining gene SRY and these genes play key roles during animal developme nt. We report here cloning and characterisation of the human SOX18 gene. SO X18 gene is expressed in foetal brain as well as in a wide range of foetal, and adult tissues indicating its function is not restricted to early develo pment. Mapping analysis has revealed that SOX18 gene is located on human ch romosome 20q13.3, 27.29 cR distal from the marker D20S173. (C) 2000 Elsevie r Science B.V. All rights reserved.