Calretinin co-localizes with the NMDA receptor subunit NR1 in cholinergic amacrine cells of the rat retina

Authors
Araki, CM Hamassaki-Britto, DE
Citation
Cm. Araki et De. Hamassaki-britto, Calretinin co-localizes with the NMDA receptor subunit NR1 in cholinergic amacrine cells of the rat retina, BRAIN RES, 869(1-2), 2000, pp. 220-224
Citations number
35
Categorie Soggetti
Neurosciences & Behavoir
Journal title
BRAIN RESEARCH
ISSN journal
00068993 → ACNP
Volume
869
Issue
1-2
Year of publication
2000
Pages
220 - 224
Database
ISI
SICI code
0006-8993(20000630)869:1-2<220:CCWTNR>2.0.ZU;2-6
Abstract
Immunohistochemistry was used to verify whether choline-acetiltransferase c olocalizes with calcium-binding proteins and NMDA receptor subunit NR1 in t he rat retina. Whereas calbindin and parvalbumin were not observed in choli nergic amacrine cells, calretinin and NR1 were very frequently colocalized with ChAT. Calretinin/NR1-positive cells were also shown, suggesting that c alretinin in cholinergic cells of the rat may be related to the buffering o f excess intracellular calcium generated by activation of NMDA receptors. ( C) 2000 Elsevier Science B.V. All rights reserved.