Depigmented hypertrichosis following Blaschko's lines associated with cerebral and ocular malformations: a new neurocutaneous, autosomal lethal gene syndrome from the group of epidermal naevus syndromes?

The lines of Blaschko represent one of the cutaneous patterns of mosaicism followed by various skin disorders. Developmental abnormalities affecting o ther tissues derived from the embryonic ectoderm and mesoderm are occasiona lly associated. We describe a 30-year-old man with depigmented, bilateral h ypertrichosis and dilated follicular orifices following Blaschko's lines as sociated with cerebral and ocular malformations. The findings suggest a pre viously unreported neurocutaneous, autosomal lethal gene syndrome from the group of epidermal naevus syndromes.