The role of coronary stenting in improving outcomes after failed thrombolys
is has not been well described. This study represents a registry of rescue
coronary interventions performed during a 3 year period in which interventi
onal treatment was changing for this high risk population. We analyzed acut
e angiographic results and clinical outcomes in 108 consecutive patients tr
eated for thrombolytic failure with either balloon angioplasty (n = 63) or
coronary stenting (n = 45). The overall in-hospital mortality rate was 5.5%
, and there was no increase in complications in the stent group. Coronary s
tenting was associated with improved angiographic results including lower r
esidual stenosis in the culprit artery (15 +/- 10% vs. 31 +/- 22%, P < 0.00
1) without increasing bleeding complications. The rate of in-hospital and l
ong term target vessel revascularization in the stent group was significant
ly lower than in the unmatched PTCA group. Rescue coronary stenting is safe
, improves acute angiographic results compared to PTCA alone and leads to e
xcellent in-hospital and long term outcomes. (C) 2000 Wiley-Liss, Inc.