RESULTS AND VIEWS OF WOMEN IN POPULATION-WIDE PREGNANCY SCREENING FORTRISOMY-21 IN EAST FINLAND

The serum screening test for trisomy 21 was offered to all pregnant wo men in East Finland during 1993. The results and the women's views on trisomy screening are reported here. A total of 9,343 (89%) of the pre gnant women participated in the screening. A total of 615 women were e ligible for amniocentesis or chorionic villus sampling; among them 22 pregnancies were affected by Down syndrome. Fifteen of them were detec ted by double screening; in 2 missed cases only maternal-serum alpha-f etoprotein had been determined. In all 5 cases missed by double screen ing the maternal age was less than 30 years. The women's attitudes wer e studied by means of a questionnaire, which was mailed to 214 women. The response rate to our questionnaire was 74%. A total of 87% of resp ondents highly or very highly valued the opportunity to participate in the screening. Despite the existing problems caused by late testing, 87% of respondents want to be tested again in their future pregnancies .