Background-Virtual reality techniques have recently been introduced into cl
inical medicine, This study examines the possibility of coronary artery fly
-through using a dataset obtained by noninvasive coronary angiography with
contrast-enhanced electron-beam computed tomography,
Methods and Results-Ten patients were examined, and 40 to 60 transaxial tom
ograms (thickness, 1.5 mm; in-plane pixel dimensions, approximate to 0.5x0.
5 mm) were obtained after intravenous contrast injection. The datasets were
processed on a graphics workstation using volume-rendering software. For f
ly-throughs, the contrast-enhanced lumen was made transparent and other tis
sue was made opaque. Then, key frames were selected in a path through the v
essel, with software interpolation of frames between key frames. A typical
movie contained 150 to 300 frames (10 to 15 key frames). Fly-throughs of co
ronary bypass grafts (n=3), left anterior descending arteries (LAD; n=6), a
nd the intermediate branch (n=1) were reconstructed. Coronary calcification
s were seen in 3 patients. The fly-through of the intermediate branch, the
bypass grafts, and one of the LADs did not show any irregularities. In 2 ca
ses, a stenosis was visible in the LAD; its presence was confirmed by conve
ntional coronary angiography.
Conclusions-Recent developments in fast-volume rendering using special-purp
ose hardware in combination with noninvasive coronary angiography with elec
tron beam computed tomography have provided the possibility of performing c
oronary artery fly-throughs.