This paper reviews the recent literature on the juvenile spondyloarthropath
ies, Several case reports emphasized clinical characteristics of the spondl
yoarthropathies including reactive arthritis, MR imaging seemed to enhance
the detection of sacroiliitis in children with spondyloarthropathies. The p
resence of different cytokines in various forms of juvenile arthritis inclu
ding the juvenile spondyloarthropathies was investigated and suggested a ro
le for the anti-inflammatory cytokines in milder disease, Evidence for the
association of low-molecular-weight polypeptide gene polymorphism with susc
eptibility to acute anterior uveitis was found in a Mexican population of p
atients with spondyloarthropathies, including 80 with juvenile spondyloarth
ropathy, A review of therapeutic use of sulfasalazine in children with chro
nic arthritis, including those with juvenile spondyloarthropathy, concluded
that it was safe and effective. Last, a study assessed aerobic fitness and
physical activity in patients with juvenile spondyloarthropathy in remissi
on and suggested a decline in physical fitness in older patients. (C) 2000
Lippincott Williams & Wilkins, Inc.