Current recommendations for biopsy of a pigmented skin lesion suspected of
being melanoma include complete excision when possible. Because benign pigm
ented lesions do not warrant excisional biopsy, especially when they are la
rge and/or on cosmetically sensitive sites, incisional biopsy is desirable.
For such lesions we recommend a fusiform incisional biopsy. This tissue sa
mpling technique not only yields an excellent cosmetic outcome, but also pr
ovides the pathologist with an optimal biopsy specimen in which he/she can
assess the symmetry, circumscription, breadth, and depth of the lesion.