INTRAMOLECULAR 1,3-DIPOLAR CYCLOADDITION AS A TOOL FOR THE PREPARATION OF AZASPIROCYCLIC KETO AZIRIDINES - SYNTHESIS OF INTERMEDIATES FOR THE TOTAL SYNTHESIS OF (+ -)-CEPHALOTAXINE/

Authors
MOLANDER GA HIERSEMANN M
Citation
Ga. Molander et M. Hiersemann, INTRAMOLECULAR 1,3-DIPOLAR CYCLOADDITION AS A TOOL FOR THE PREPARATION OF AZASPIROCYCLIC KETO AZIRIDINES - SYNTHESIS OF INTERMEDIATES FOR THE TOTAL SYNTHESIS OF (+ -)-CEPHALOTAXINE/, Tetrahedron letters, 38(25), 1997, pp. 4347-4350
Citations number
62
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
25
Year of publication
1997
Pages
4347 - 4350
Database
ISI
SICI code
0040-4039(1997)38:25<4347:I1CAAT>2.0.ZU;2-2
Abstract
The thermal intramolecular azide-enone 1,3-dipolar cycloaddition to az aspirocyclic keto aziridines 17 and 18 is reported, alpha-Hydroxylatio n and oxidation to the corresponding diketo aziridine 2 provided an in termediate in a synthetic approach toward cephalotaxine 1. (C) 1997 El sevier Science Ltd.