SYNTHESIS OF A MODEL OF CHLOROPEPTIN-I, CHLOROPEPTIN-II WESTERN SUBUNIT BY THE INTRAMOLECULAR SNAR BASED METHODOLOGY

Authors
ROUSSI G ZAMORA EG CARBONNELLE AC BEUGELMANS R
Citation
G. Roussi et al., SYNTHESIS OF A MODEL OF CHLOROPEPTIN-I, CHLOROPEPTIN-II WESTERN SUBUNIT BY THE INTRAMOLECULAR SNAR BASED METHODOLOGY, Tetrahedron letters, 38(25), 1997, pp. 4401-4404
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
25
Year of publication
1997
Pages
4401 - 4404
Database
ISI
SICI code
0040-4039(1997)38:25<4401:SOAMOC>2.0.ZU;2-H
Abstract
Formation of a biaryl ether bond between the termini of a tetrapeptide containing a highly racemization prone amino acid by the intramolecul ar SNAr reaction afforded two diastereomeric 16-membered macrocycles a long with their respective atropoisomers. The (R,S,R) and its atropois omer constituted a model of chloropeptins I, II western part. (C) 1997 Published by Elsevier Science Ltd.