REACTION OF N-[BIS(METHYLTHIO)METHYLENE]GLYCINATES WITH ELECTRON-DEFICIENT ALKYNES, SYNTHESIS OF (Z)-ALPHA,BETA-DIDEHYDROGLUTAMIC ACID-DERIVATIVES

Authors
ALVAREZIBARRA C CSAKY AG ORTEGA EM DELAMORENA MJ QUIROGA ML
Citation
C. Alvarezibarra et al., REACTION OF N-[BIS(METHYLTHIO)METHYLENE]GLYCINATES WITH ELECTRON-DEFICIENT ALKYNES, SYNTHESIS OF (Z)-ALPHA,BETA-DIDEHYDROGLUTAMIC ACID-DERIVATIVES, Tetrahedron letters, 38(25), 1997, pp. 4501-4502
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
25
Year of publication
1997
Pages
4501 - 4502
Database
ISI
SICI code
0040-4039(1997)38:25<4501:RONWE>2.0.ZU;2-X
Abstract
The addition of either the alkaline enolates of the glycinates 1 or th eir naked enolates to electron defficient alkynes allows for the synth esis of substituted (Z)-alpha,beta-didehydroglutamic acid derivatives 7 via a Michael addition/1,3-prototropic rearrangement sequence. (C) 1 997 Elsevier Science Ltd.