Alkylation and related electrophilic reactions at endocyclic nitrogen atoms in the chemistry of tetrazoles

This review summarizes the results of studies of reactions between tetrazol es and various electrophilic agents, published over the past twenty years. Where possible, mechanisms of the reactions are discussed in detail and con sideration is given to how the rate and selectivity of processes are influe nced by the nature of reactants, parameters of reaction medium, and by othe r factors.