Based on the idea of quasi-interpolation and radial basis functions approxi
mation, a numerical method is developed to quasi-interpolate the forcing te
rm of differential equations by using radial basis functions. A highly accu
rate approximation for the solution can then be obtained by solving the cor
responding fundamental equation and a small size system of equations relate
d to the initial or boundary conditions. This overcomes the ill-conditionin
g problem resulting from using the radial basis functions as a global inter
polant. Error estimation is given for a particular second-order stiff diffe
rential equation with boundary layer. The result of computations indicates
that the method can be applied to solve very stiff problems. With the use o
f multiquadric, a special class of radial basis functions, it has been show
n that a reasonable choice for the optimal shape parameter is obtained by t
aking the same value of the shape parameter as the perturbed parameter cont
ained in the stiff equation. Copyright (C) 2000 John Wiley & Sons, Ltd.