We tested a theoretical model that posited direct and interactive relations
hips between personality and environment as predictive of problem drug use.
Hierarchical regression analyses were performed on data from a nonclinical
sample of males and females first tested in adolescence and followed into
young adulthood. In main effects analyses, cross-sectional models for marij
uana and a composite of "harder" drugs strongly supported our theoretical p
erspective: several environmental and personality variables significantly p
redicted concurrent problem use. Longitudinal analyses produced mixed resul
ts, with either smaller numbers of significant personality/environment pred
ictors or personality predictors dropping out completely. Peer drug use and
depression best predicted problem "hard" drug use, while motivations to us
e with others and disinhibition best predicted problem marijuana use. Perso
nality/peer group interactions were significant both cross-sectionally and
longitudinally, indicating that membership in a problem-using social networ
k enhanced the predictive ability of, or helped bring to fruition, several
personality predisposers.