Patients treated by open carpal tunnel decompression under local anaestheti
c experience significant pain with the introduction of local anaesthetic be
fore operation. A prospective double-blind randomized placebo controlled tr
ial was carried out to assess whether this pain could be reduced with the p
re-application of a topical lignocaine-prilocaine anaesthetic cream. Ninete
en patients undergoing simultaneous bilateral operations were studied. Pain
, measured with a visual analogue scale, was significantly reduced on the s
ides treated with anaesthetic cream. On a four point verbal scale the ratin
g on the placebo side was "moderate' or "severe", compared to "mild" on the
anaesthetic cream side. The reduction in pain was greater in women, possib
ly due to a relatively thinner dermis, There were no adverse effects.