Chiral pyridinyl-oxazolines as ligands for copper(I)-catalyzed asymmetric cyclopropanation

Citation
Xy. Wu et al., Chiral pyridinyl-oxazolines as ligands for copper(I)-catalyzed asymmetric cyclopropanation, J MOL CAT A, 157(1-2), 2000, pp. 59-63
Citations number
8
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
ISSN journal
13811169 → ACNP
Volume
157
Issue
1-2
Year of publication
2000
Pages
59 - 63
Database
ISI
SICI code
1381-1169(20000620)157:1-2<59:CPALFC>2.0.ZU;2-B
Abstract
New chiral ligands containing oxazoline unit and pyridine separated by a me thylene group 3 have been synthesized from enantiomerically pure amino alco hols and 2-picoline using a convenient procedure. Comparative investigation of ligands 3 with chiral conjugate pyridinyl-oxazoline ligands 2 and quino linyl-oxazoline ligands 1 in copper(I)-catalyzed asymmetric cyclopropanatio n of styrene with diazoacetates was described. (C) 2000 Elsevier Science B. V. All rights reserved.