Simple synthesis of benzofuranoid neolignans from Myristica fragrans

Authors
Juhasz, L Kurti, L Antus, S
Citation
L. Juhasz et al., Simple synthesis of benzofuranoid neolignans from Myristica fragrans, J NAT PROD, 63(6), 2000, pp. 866-870
Citations number
21
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
6
Year of publication
2000
Pages
866 - 870
Database
ISI
SICI code
0163-3864(200006)63:6<866:SSOBNF>2.0.ZU;2-P
Abstract
The total synthesis of four neolignans-fragnasols A (1), B (2), and C (3) a nd dehydrodiisoeugenol (4)-starting from the readily available phenol deriv ative isoeugenol (5) was accomplished. The key step of the synthesis of the se natural products is a novel type of dimerization of 5 into 4 with iodobe nzene diacetate.