Ma. Dam et al., High-yield formation of giant bis(bicyclic) and crypt-tris(bicyclic) molecules under normal reaction conditions, J ORG CHEM, 65(13), 2000, pp. 3941-3946
We report the unexpected result of the reaction of 1,3-bis[(9-anthrylmethox
y)methyl]benzene (1a) or 1,3,5 -tris [(9-anthrylmethoxy)methyl]benzene (1b)
with tris(2-maleimidoethyl)amine (2) in homogeneous solution leading to gi
ant bis(bicyclic) and crypt-tris(bicyclic) molecules. The anticipated, intr
actable solids are obtained in a condensed state reaction using an oscillat
ing mill.