Intravascular lymphoma presenting as bilateral panophthalmitis and retinaldetachment in a dog

A seven-year-old, spayed female boxer was presented for sudden blindness an d red eyes of one week's duration. Ophthalmic examination revealed bilatera l uveitis with complete bullous retinal detachments. Initial diagnostic tes ting failed to reveal evidence of systemic disease. Cytopathology of subret inal aspirates confirmed the presence of macrophages with intracytoplasmic retinal pigment, epithelial and choroidal pigment, and monocytes, Tentative diagnoses were idiopathic uveitis and retinal detachment. The dog was trea ted with immunosuppressive doses of prednisone. The retinas reattached and vision returned. By two months, the dog became blind and systemically ill. Postmortem and histopathological examinations revealed intravascular lympho ma in multiple organs, including the eyes.