Algorithms for mutant sorting: the need for phenotype vocabularies

For effectively annotated phenotypes for mouse, a number of detailed phenot ypic classification systems are needed. The rapidly increasing number of ph enotypically described characteristics of both normal and mutant mice are p roviding a rich data set for comparison and analysis. However, we cannot re ly on text descriptions that are subject to the word-usage style of the: wr iter if we are to do large-scale comparative analysis of traits and disease s. The rationale for developing vocabularies and examples of several vocabu laries being developed are described. Finally, the critical nature of commu nity participation in both building and applying phenotype vocabularies is discussed.