Radical cyclization of beta-aminoacrylates: Synthesis of (-)-indolizidine 223AB

Authors
Lee, E Jeong, EJ Min, SJ Hong, S Lim, J Kim, SK Kim, HJ Choi, BG Koo, KC
Citation
E. Lee et al., Radical cyclization of beta-aminoacrylates: Synthesis of (-)-indolizidine 223AB, ORG LETT, 2(14), 2000, pp. 2169-2171
Citations number
26
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
14
Year of publication
2000
Pages
2169 - 2171
Database
ISI
SICI code
1523-7060(20000713)2:14<2169:RCOBSO>2.0.ZU;2-6
Abstract
[GRAPHICS] (-)-Indolizidine 223AB was synthesized via radical cyclization of the beta- aminoacrylate derivative of a trans-2,5-disubstituted pyrrolidine. The tran s-2,5-disubstituted pyrrolidine substrate was prepared by radical cyclizati on of a Ses protected beta-aminoacrylate.