Squamous cell carcinoma (SCC) arising in the skeletal muscle is rare. A cas
e of a 19-year-old female patient with an intramuscular forearm tumor showi
ng a histopathologically overwhelming squamous element is presented. Micros
copic examination revealed the classical features of SCC, including horn pe
arls, individual cell keratinization and intercellular bridge. A malignant
spindle cell component was not detected. Neither evidence of another primar
y site nor skin lesion over the tumor was found and no metastatic lesion wa
s detected in the 5 years since the appearance of the mass.