Cardiac troponin I in fulminant adenovirus myocarditis treated with a 24-hour infusion of high-dose intravenous immunoglobulin

Citation
G. Briassoulis et al., Cardiac troponin I in fulminant adenovirus myocarditis treated with a 24-hour infusion of high-dose intravenous immunoglobulin, PEDIAT CARD, 21(4), 2000, pp. 391-394
Citations number
10
Categorie Soggetti
Pediatrics
Journal title
PEDIATRIC CARDIOLOGY
ISSN journal
01720643 → ACNP
Volume
21
Issue
4
Year of publication
2000
Pages
391 - 394
Database
ISI
SICI code
0172-0643(200007/08)21:4<391:CTIIFA>2.0.ZU;2-E
Abstract
We report a successful outcome on an acute adenovirus myocarditis treated w ith a 24-hour high-dose intravenous immunoglobulin (24-HDIVIG) in a 4.5-yea r-old girl. A postviral etiology of acute myocarditis was assessed on the b asis of the polymerase chain reaction technique. Among other early markers of cardiac injury, cardiac isoform of troponin-I (cTnI) was significantly c orrelated to the left ventricular ejection fraction (r = -0.86, p < 0.0001) , Follow-up of cTnI, which might also be correlated to the short-term outco me, allows fast, easy, and noninvasive estimation of response to the aggres sive treatment with 24-HDIVIG in acute adenovirus myocarditis in children.