Anti-inflammatory and immunologically active polysaccharides of Periandra mediterranea

Authors
Pereira, BMR da Silva, BP Pereira, NA Parente, JP
Citation
Bmr. Pereira et al., Anti-inflammatory and immunologically active polysaccharides of Periandra mediterranea, PHYTOCHEM, 54(4), 2000, pp. 409-413
Citations number
23
Categorie Soggetti
Agricultural Chemistry","Animal & Plant Sciences
Journal title
PHYTOCHEMISTRY
ISSN journal
00319422 → ACNP
Volume
54
Issue
4
Year of publication
2000
Pages
409 - 413
Database
ISI
SICI code
0031-9422(200006)54:4<409:AAIAPO>2.0.ZU;2-1
Abstract
Three polysaccharides, glucans with mean M-r's of 1.5 x 10(5), 3.6 x 10(4) and 2.1 x 10(4), were isolated from dried roots of Periandra mediterranea b y fractionation on Sephacryl S-300 HR and Sephadex G-25. Chemical and spect roscopic studies indicated that they have a highly branched glucan type str ucture composed of alpha-(1 --> 4) linked D-glucopyranose residues with bot h (3 --> 4) and (4 --> 6) branching points. The polysaccharides enhance pha gocytosis in vivo, and exhibit anti-inflammatory activity. (C) 2000 Elsevie r Science Ltd. All rights reserved.