This 2-year longitudinal study assessed prevalence of Axis I anxiety disord
ers and anxiety symptoms and their relationship to manifestations of HIV il
lness in a sample of nonintravenous drug users. The sample included 173 hom
osexual men with HIV or AIDS (HIV+/AIDS) and 84 homosexual men negative for
HIV or AIDS (HIV-). Data were compared with national prevalence rates to p
rovide a framework for interpretation. No significant differences were obse
rved, However compared with the general population, both HIV+/AIDS and HIV-
men reported more anxiety symptoms and stress. For the HIV+/AIDS group the
re was a positive relationship between anxiety and HIV symptoms, fatigue, a
nd physical limitations. No changes in rates or levels of anxiety were obse
rved in those whose immunologic markers improved or worsened over the 2 yea
rs.