Sa. Osadchii et al., Study of alkaloids from plants of Siberia and Altai 4. N-deethylation of diterpene alkaloids of the aconitane type, RUSS CHEM B, 49(3), 2000, pp. 557-562
A method for N-deethylation of diterpene alkaloids of the aconitane type by
the Cope reaction was developed using conversions of lappaconitine and ela
tine as examples. The previously unknown nitrones of N-deethylated lappacon
itine, elatine, and elatidine were prepared.