Synthesis of the scalemic form of alkaloid (-)-dipthocarpamine

Authors
Karpyshev, NN Tolstikov, AG Tolstikova, OV Yakovleva, OD Shmakov, VS
Citation
Nn. Karpyshev et al., Synthesis of the scalemic form of alkaloid (-)-dipthocarpamine, RUSS CHEM B, 49(3), 2000, pp. 569-570
Citations number
9
Categorie Soggetti
Chemistry
Journal title
RUSSIAN CHEMICAL BULLETIN
ISSN journal
10665285 → ACNP
Volume
49
Issue
3
Year of publication
2000
Pages
569 - 570
Database
ISI
SICI code
1066-5285(200003)49:3<569:SOTSFO>2.0.ZU;2-Y
Abstract
The scalemic form of active alkaloid (-)-dipthocarpamine was synthesized by asymmetric oxidation of N-isopropyl-N'-(methylthiohexyl)urea with hydrogen peroxide in the presence of vanadium(iv) complexes with chiral Shiffs base s.