To regulate the perfusion now rate of a centrifugal blood pump, a micr
ocomputer controller was developed. The computer monitored the flow ra
te of the pump with an electromagnetic flowmeter or an ultrasonic puls
e Doppler flowmeter, rotational speed of the pump, aortic pressure, an
d the amount of blood in a reservoir. A discrete integral controller w
ith a control interval of 1 s was adopted for the controller. For the
safety of the control system, we added functions for detecting a clamp
on the tubing, a dislocation of the flow sensor, or an inverse direct
ion of the flow sensor. During a standby period, the computer calculat
ed the rotational speed from aortic pressure to minimize the forward o
r the backward flow at the start of the pump perfusion. The automatic
flow controller was used on 5 patients during cardiac operations and m
aintained the flow rate within +/-6% of the set point.