CLINICAL-EVALUATION OF THE CENTRIFUGAL PUMP IN OPEN-HEART-SURGERY - ACOMPARATIVE-STUDY OF DIFFERENT PUMPS

The centrifugal pump is now widely used in open heart surgery for its clinical benefits related to the blood elements and the coagulation sy stem. The purpose of this study was to compare the clinical performanc es of and the outcomes offered by 4 types of centrifugal pumps. For ea ch pump, we investigated the effects on the blood elements, coagulatio n system, complements, and immunoglobulins during open heart surgery. Four types of centrifugal pumps were used: the HPM-15 (Nikkiso Co.), t he Capiox (Terumo Co.), the Lifestream (St. Jude Medical Co.), and the BP-80 (Medtronic, BioMedicus Co.). The platelet count, lactate dehydr ogenase (LDI-I), antithrombin III (AT III), thrombin-antithrombin comp lex (TAT), complements (C3, C4 and CH50), and immunoglobulins (IgG, Ig A, and IgM) were measured before and after cardiopulmonary bypass (CPB ). The platelet count was decreased more significantly by the HPM-15 t han by any of the other pumps. The other parameters showed no differen ce among the 4 pumps. In clinical use, each of the 4 types of centrifu gal pumps was safe.