COMPARISON OF THE GYRO-C1E3 AND BIOMEDICUS-CENTRIFUGAL-PUMP PERFORMANCES DURING CARDIOPULMONARY BYPASS

The compact eccentric inlet port (C1E3) centrifugal blood pump was dev eloped as a cardiopulmonary bypass (CPB) pump. The C1E3 pump incorpora ted a seal-less design with a blood stagnation free structure. The pum p impeller was magnetically coupled to the driver magnet in a seal-les s manner. To develop an atraumatic and antithrombogenic centrifugal pu mp without a shaft seal junction, a double pivot bearing system was in troduced. Recently, a mass production model of the C1E3 was fabricated and evaluated. The ratio of the normalized index of hemolysis (NIH) o f the C1E3 was 0.007 g/100 L, in comparison to the NIH of the BP-80, 0 .018 g/100 L, each in a CPB condition of 5 L/min against 325 mm Hg. Bo th pumps were compared in identical in vitro circuits. To further eval uate the pumps during cardiopulmonary bypass for reliability and funct ion, 6 h of CPB was performed on each of 8 bovines using either the C1 E3 or BP-80 centrifugal pump. The BP-80 and C1E3 provided pump flows o f 50-60 ml/kg/min without incident. The hemodynamics were stable, and the hematology and biochemistry data were within normal ranges. There were no statistically significant differences between the 2 groups. Co ncerning the plasma free hemoglobin values, a mass production model of the C1E3 pump had the same hemolysis levels as the BP-80. Our prelimi nary studies reveal that the C1E3 pump is reliable. Also, the C1E3 wil l satisfy clinical requirements as a cardiopulmonary bypass pump.