The objective of the present study was to estimate the strength of the asso
ciations between recent weapon carrying and alcohol, cigarette, and illicit
drug use among US Virgin Islands (USVI) youth. Data from 1,124 students in
Grades 7-12 were analyzed using the conditional form of multiple logistic
regression. Compared with youth who did not carry a weapon, youth who carri
ed a weapon were more likely to be male and recent cigarette, alcohol, and
illicit drug users. After matching on school and controlling for age, sex,
race, neigborhood characteristics, and affiliation with friends who use alc
ohol and illegal drugs, the associations with cigarette smoking and illicit
drug use remained both moderate and statistically significant (odds ratio
[OR] = 4.31, p < .001; OR = 2.99, p < .001, respectively). These findings i
dentify a potentially high-risk population that could be targeted for inter
ventions to reduce weapon carrying among youth.