Assignments of the tyrosinase related protein-1 and-2 genes to human chromosome bands 9p23 and 13q32.1 by in situ hybridization

Authors
Lee, YM Ha, MJ Ryu, MS Moon, E Im, S Kim, HJ Kim, W
Citation
Ym. Lee et al., Assignments of the tyrosinase related protein-1 and-2 genes to human chromosome bands 9p23 and 13q32.1 by in situ hybridization, YONSEI MED, 41(3), 2000, pp. 398-400
Citations number
11
Categorie Soggetti
General & Internal Medicine
Journal title
YONSEI MEDICAL JOURNAL
ISSN journal
05135796 → ACNP
Volume
41
Issue
3
Year of publication
2000
Pages
398 - 400
Database
ISI
SICI code
0513-5796(200006)41:3<398:AOTTRP>2.0.ZU;2-I
Abstract
To determine the precise chromosomal localization of tyrosine related prote in-1 and -2 (TRP-1 and TRP-2) genes by fluorescence in situ hybridization, we used DNAs isolated from human bacterial artificial chromosome clones. Th ey contain genomic sequences with approximately 120 kb inserts for TRP-1 an d TRP-2. The TRP-1 and TRP-2 genes were assigned to human chromosome bands 9p23 and 13q32.1, respectively. These results confirmed the previously mapp ed location for the TRP-1 gene and more precisely located the TRP-2 gene, w hich had previously been mapped to chromosome 13q31-q32.